Study of beta-catenin induced liver tumorigenesis in a Met-Nrf2 mouse model.
Ongoing research at the Organ Pathobiology and Therapeutics Institute investigating beta-catenin driven tumor formation in the liver, using a Met-Nrf2 mouse model.
Tissue samples are analyzed via immunohistochemistry to assess pathway activation and tumor characteristics. Findings are interpreted in the context of established hepatocellular carcinoma signaling pathways.
Project is ongoing. Detailed findings and figures to be added as the work progresses.